Technical Platform
Fully Human Discovery and Engineering Platform
● Highly diversified nature antibody library, starting with PBMC, bone marrows and spleen samples from hundreds of donors.
● Fortified and enhanced with the addition of semi-synthetic library, fully synthetic library and human single-domain antibody library.
● Proprietary design of fully synthetic library to improve the developability for discovery of antibody drugs.
● Over 100 billion independent clones, which makes it one of the largest library in industry. High affinity clones, such as nM or sub nM, can be selected directly from the library without further affinity maturation.
● High-affinity antibodies binding to membrane proteins with native conformation can be directly enriched by combination of protein panning and cell panning technologies.
● The best candidates can be characterized and selected in multiple formats, such as phage, scFv, IgG.
